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The best anti-ageing technique could be standing up, scientists believe, after discovering that spending more time on two feet protects DNA.
A study found that too much sitting down shortens telomeres, the protective caps which sit at the end of chromosomes.
Short telomeres have been linked to premature ageing, disease and early death. So spending less time on the sofa could help people live longer by preventing their DNA from ageing.
The research found that people who were frequently on their feet had longer telomeres, which were keeping the genetic code safe from wear and tear.
Intriguingly taking part in more exercise did not seem to have an impact on telomere length.
Prof Mai-Lis Hellenius, from Karolinska University Hospital in Stockholm, said : "In many countries formal exercise may be increasing, but at the same time people spend more time sitting.
"There is growing concern that not only low physical activity but probably also sitting and sedentary behaviour is an important and new health hazard of our time.
"We hypothesise that a reduction in sitting hours is of greater importance than an increase in exercise time for elderly risk individuals."
Telomeres stop chromosomes from fraying, clumping together and "scrambling" genetic code.
Scientists liken their function to the plastic tips on the ends of shoelaces, and say that lifespan is linked to their length.
Researchers looked at 49 overweight sedentary adults in their late sixties and measured the length of the telomeres in their blood cells.
Half of them had been part of an exercise programme that lasted six months, while the other half had not.
Physical activity levels were assessed using a diary and pedometer to measure the amount of footsteps taken each day.
The amount of time spent sitting down was worked out through a questionnaire.
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科學(xué)家發(fā)現(xiàn),最好的抗衰老技術(shù)可能就是站起來,別“坐以待斃”??茖W(xué)家研究發(fā)現(xiàn),雖然鍛煉越多的人往往更健康,但是最重要的因素還是坐著的時(shí)間長短。長時(shí)間坐著會(huì)縮短端粒——染色體末端的保護(hù)帽。
端粒縮短會(huì)導(dǎo)致早衰、疾病甚至早逝,因此減少坐在沙發(fā)上的時(shí)間可以幫助防止DNA衰老,延長壽命。
研究發(fā)現(xiàn)經(jīng)常站立的人,端粒往往更長,可以減少遺傳密碼磨損。
一個(gè)人坐著的時(shí)間越少,他的端粒就越長,他就越可能長壽。有趣的是,多鍛煉身體似乎對(duì)端粒的長度并沒有影響。
瑞典斯德哥爾摩的卡羅林斯卡醫(yī)學(xué)院的海勒紐斯(Mai-Lis Hellenius)教授說:“在許多國家,正式的鍛煉也許越來越多,但同時(shí)人們坐著的時(shí)間也越來越多?!?/p>
“引起越來越多的擔(dān)憂的不僅僅是體育鍛煉時(shí)間少,久坐行為也是我們這個(gè)時(shí)代新的重大健康隱憂。”
“我們認(rèn)為對(duì)于早衰人群來說,減少坐著的時(shí)間比增加運(yùn)動(dòng)時(shí)間來得更加重要?!?/p>
端粒能夠使染色體避免磨損、凝結(jié)以及“擾亂”遺傳密碼。
科學(xué)家將端粒的功能比作鞋帶的塑料頭,稱壽命長短與端粒長短相關(guān)。
研究人員觀察了49名六七十歲的肥胖久坐人士,并測(cè)量了血液細(xì)胞中的端粒長短。他們中有一半的人參與鍛煉計(jì)劃至少長達(dá)六個(gè)月,另一半的人則沒有參加。
研究人員通過記錄日記以及使用步程計(jì)來測(cè)量每天走了多少步,以此來評(píng)估鍛煉強(qiáng)度水平。
而坐著的時(shí)間則通過調(diào)查問卷的方式統(tǒng)計(jì)。
(譯者 陳迪BFSUMTI 編輯 丹妮)
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